A new Defective Helper RNA to produce recombinant Sindbis virus that infects neurons but does not propagate

• المؤلفون الرئيسيون: Justus M Kebschull (مؤلف), Pedro eGarcia da Silva (مؤلف), Anthony M Zador (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2016-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Recombinant Sindbis viruses are important tools in neuroscience because they combine rapid and high transgene expression with a capacity to carry large transgenes. Currently, two packaging systems based on the DH(26S)5'SIN and the DH-BB(tRNA;TE12) Defective Helper (DH) RNAs are available for ge...