Monocarbonyl Curcumin Analogues as Potent Inhibitors against Human Glutathione Transferase P1-1

• मुख्य लेखकों: Panagiota Pantiora (लेखक), Veronika Furlan (लेखक), Dimitris Matiadis (लेखक), Barbara Mavroidi (लेखक), Fereniki Perperopoulou (लेखक), Anastassios C. Papageorgiou (लेखक), Marina Sagnou (लेखक), Urban Bren (लेखक), Maria Pelecanou (लेखक), Nikolaos E. Labrou (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The isoenzyme of human glutathione transferase P1-1 (hGSTP1-1) is involved in multi-drug resistance (MDR) mechanisms in numerous cancer cell lines. In the present study, the inhibition potency of two curcuminoids and eleven monocarbonyl curcumin analogues against hGSTP1-1 was investigated. Demethoxy...