Development of depot PLGA-based in-situ implant of Linagliptin: Sustained release and glycemic control

• Main Authors: Eman Gomaa (Author), Noura G. Eissa (Author), Tarek M. Ibrahim (Author), Hany M. El-Bassossy (Author), Hanan M. El-Nahas (Author), Margrit M. Ayoub (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High percentage of diabetic people are diagnosed as type 2 who require daily dosing of an antidiabetic drug such as Linagliptin (Lina) to manage their blood glucose levels. This study aimed to develop injectable Lina-loaded biodegradable poly (lactic-co-glycolic acid) (PLGA) in-situ implants (ISIs)...