Development of depot PLGA-based in-situ implant of Linagliptin: Sustained release and glycemic control

• Autores principales: Eman Gomaa (Autor), Noura G. Eissa (Autor), Tarek M. Ibrahim (Autor), Hany M. El-Bassossy (Autor), Hanan M. El-Nahas (Autor), Margrit M. Ayoub (Autor)
• Formato: Libro
• Publicado: Elsevier, 2023-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

High percentage of diabetic people are diagnosed as type 2 who require daily dosing of an antidiabetic drug such as Linagliptin (Lina) to manage their blood glucose levels. This study aimed to develop injectable Lina-loaded biodegradable poly (lactic-co-glycolic acid) (PLGA) in-situ implants (ISIs)...