Derinat® has an immunomodulatory and anti-inflammatory effect on the model of acute lung injury in male SD rats

• Main Authors: Yulia A. Palikova (Author), Victor A. Palikov (Author), Nadezhda I. Novikova (Author), Gulsara A. Slashcheva (Author), Ekaterina A. Rasskazova (Author), Elena A. Tukhovskaya (Author), Alexey V. Danilkovich (Author), Igor A. Dyachenko (Author), Alexey A. Belogurov Jr (Author), Anna A. Kudriaeva (Author), Daniil Y Bugrimov (Author), Olga N. Krasnorutskaya (Author), Arkady N. Murashev (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To simulate acute lung injury (ALI) in SD male rats they we administered intratracheally with lipopolysaccharide (LPS) followed by hyperventilation of the lungs (HVL), which lead to functional changes in the respiratory system and an increase in the blood serum concentration of inflammatory cytokine...