Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition

• Main Authors: Schlichter Rémy (Author), Freund-Mercier Marie (Author), Vergnano Angela (Author), Uhl-Bronner Sandra (Author), Veinante Pierre (Author), Breton Jean-Didier (Author), Poisbeau Pierrick (Author)
• Format: Book
• Published: SAGE Publishing, 2008-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Recent evidence suggests that oxytocin (OT), secreted in the superficial spinal cord dorsal horn by descending axons of paraventricular hypothalamic nucleus (PVN) neurons, produces antinociception and analgesia. The spinal mechanism...