The influence of detoxification agents on the intensity of side effects caused by medium-high doses of methotrexate in children with acute lymphoblastic leukemia: Case series

• Main Authors: Šumar Jovana S. (Author), Rašković Aleksandar L. (Author), Kolarović Jovanka L. (Author), Milanović Isidora M. (Author), Konstantinidis Nada V. (Author), Milijašević Boris Ž. (Author), Mikov Momir M. (Author), Sabo Ana J. (Author)
• Format: Book
• Published: Srpsko lekarsko drustvo, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective The treatment of childhood acute lymphoblastic leukemia (ALL) in Serbia is conducted according to protocol ALL IC BMF-2009. The therapy includes the application of cytostatic drugs methotrexate and 6-mercaptopurine, and drug detoxifying Calcium Folinate. At the moment, 80% of affected chil...