Evolution of Our Understanding of XIAP Deficiency

• Main Authors: Anne C. A. Mudde (Author), Claire Booth (Author), Rebecca A. Marsh (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

X-linked inhibitor of apoptosis (XIAP) deficiency is a rare inborn error of immunity first described in 2006. XIAP deficiency is characterised by immune dysregulation and a broad spectrum of clinical manifestations, including haemophagocytic lymphohistiocytosis (HLH), inflammatory bowel disease (IBD...