A xCT role in tumour-associated ferroptosis shed light on novel therapeutic options

• প্রধান লেখক: Daniela Criscuolo (লেখক), Francesco Morra (লেখক), Angela Celetti (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Open Exploration Publishing Inc., 2022-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Solute carrier family 7 member 11 (SLC7A11; also known as xCT), a key component of the cystine/glutamate antiporter, is essential for the maintenance of cellular redox status and the regulation of tumor-associated ferroptosis. Accumulating evidence has demonstrated that xCT overexpression, resulting...