Pak2 reduction induces a failure of early embryonic development in mice

• Main Authors: Juan Zeng (Author), Nengqing Liu (Author), Yinghong Yang (Author), Yi Cheng (Author), Yuanshuai Li (Author), Xiaoxia Guo (Author), Qian Luo (Author), Lifen Zhu (Author), Hongmei Guan (Author), Bing Song (Author), Xiaofang Sun (Author)
• Format: Book
• Published: BMC, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The quality of the early embryo is vital to embryonic development and implantation. As a highly conserved serine/threonine kinase, p21-activated kinase 2 (Pak2) participates in diverse biologic processes, especially in cytoskeleton remodeling and cell apoptosis. In mice, Pak2 kno...