The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo

• প্রধান লেখক: Sara Vaccaro (লেখক), Alessandra Rossetti (লেখক), Antonella Porrazzo (লেখক), Simona Camero (লেখক), Matteo Cassandri (লেখক), Silvia Pomella (লেখক), Miriam Tomaciello (লেখক), Giampiero Macioce (লেখক), Francesca Pedini (লেখক), Giovanni Barillari (লেখক), Cinzia Marchese (লেখক), Rossella Rota (লেখক), Giovanni Cenci (লেখক), Mario Tombolini (লেখক), Robert A. Newman (লেখক), Peiying Yang (লেখক), Silvia Codenotti (লেখক), Alessandro Fanzani (লেখক), Francesca Megiorni (লেখক), Claudio Festuccia (লেখক), Giuseppe Minniti (লেখক), Giovanni Luca Gravina (লেখক), Francesca Vulcano (লেখক), Luisa Milazzo (লেখক), Francesco Marampon (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Treatment of rhabdomyosarcoma (RMS), the most common a soft tissue sarcoma in childhood, provides intensive multimodal therapy, with radiotherapy (RT) playing a critical role for local tumor control. However, since RMS efficiently activates mechanisms of resistance to therapies, despite improvements...