PK/PD Study of Mycophenolate Mofetil in Children With Systemic Lupus Erythematosus to Inform Model-Based Precision Dosing

PK/PD Study of Mycophenolate Mofetil in Children With Systemic Lupus Erythematosus to Inform Model-Based Precision Dosing

Objectives: To evaluate the mycophenolic acid [MPA, the active form of mycophenolate mofetil (MMF)] pharmacokinetic parameters in relation to clinical response to identify target exposure ranges in pediatric patients with systemic lupus erythematosus (SLE).Methods: This was a retrospective study usi...

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Main Authors: Yewei Chen (Author), Li Sun (Author), Hong Xu (Author), Min Dong (Author), Tomoyuki Mizuno (Author), Alexander A. Vinks (Author), Hermine I. Brunner (Author), Yifan Li (Author), Zhiping Li (Author)
Format: Book
Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
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