STAT3 silencing by an aptamer-based strategy hampers the crosstalk between NSCLC cells and cancer-associated fibroblasts

• Main Authors: Maria L. Ibba (Author), Giuseppe Ciccone (Author), Deborah Rotoli (Author), Gabriele Coppola (Author), Alfonso Fiorelli (Author), Silvia Catuogno (Author), Carla L. Esposito (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The identification of new effective therapeutic options for non-small-cell lung cancer (NSCLC) represents a crucial challenge in oncology. Recent studies indicate that cancer-associated fibroblasts (CAFs) participate in tumor progression by establishing a favorable microenvironment that promotes can...