STAT3 silencing by an aptamer-based strategy hampers the crosstalk between NSCLC cells and cancer-associated fibroblasts

• Autors principals: Maria L. Ibba (Autor), Giuseppe Ciccone (Autor), Deborah Rotoli (Autor), Gabriele Coppola (Autor), Alfonso Fiorelli (Autor), Silvia Catuogno (Autor), Carla L. Esposito (Autor)
• Format: Llibre
• Publicat: Elsevier, 2023-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The identification of new effective therapeutic options for non-small-cell lung cancer (NSCLC) represents a crucial challenge in oncology. Recent studies indicate that cancer-associated fibroblasts (CAFs) participate in tumor progression by establishing a favorable microenvironment that promotes can...