Exploring contractile protein mechanisms and target medications for cardiomyopathic patients with diastolic dysfunction

• Main Authors: Dustin Gerber (Author), Junjun Quan (Author), Bo Pan (Author), Xupei Huang (Author), Jie Tian (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Genetic defects have been increasingly found in cardiomyopathies, which are often present with mutations in cardiac contractile proteins. These congenital defects involve numerous intracellular pathways and share several critical clinical features, such as systolic or diastolic dysfunction...