A Novel Molecular Indicator for Inhibitor Development in Haemophilia A

• Main Authors: Esra Işık (Author), Humay Mehdiyeva (Author), Bilçağ Akgün (Author), Timur Köse (Author), Kaan Kavaklı (Author), Ferda Özkınay (Author), Tahir Atik (Author)
• Format: Book
• Published: Galenos Yayinevi, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim:Previous studies have reported inhibitor development (ID) risk in those patients who have hemophilia A (HA) with missense mutations to be 3-10%. We investigated the association between ID risk and various features of missense mutations; including the impact directly related to amino acid group c...