Early Response to the Plant Toxin Stenodactylin in Acute Myeloid Leukemia Cells Involves Inflammatory and Apoptotic Signaling

• Hoofdauteurs: Daniele Mercatelli (Auteur), Massimo Bortolotti (Auteur), Vibeke Andresen (Auteur), André Sulen (Auteur), Letizia Polito (Auteur), Bjørn Tore Gjertsen (Auteur), Andrea Bolognesi (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Stenodactylin, a highly toxic type 2 ribosome-inactivating protein purified from the caudex of Adenia stenodactyla Harms, is a potential anticancer drug candidate. Previous studies demonstrated that stenodactylin induces apoptosis and necroptosis in treated cells, involving the production of reactiv...