TGR5 deficiency activates antitumor immunity in non-small cell lung cancer via restraining M2 macrophage polarization

• Váldodahkkit: Lifang Zhao (Dahkki), Hongyan Zhang (Dahkki), Xueqing Liu (Dahkki), Shan Xue (Dahkki), Dongfang Chen (Dahkki), Jing Zou (Dahkki), Handong Jiang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2022-02-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The bile acid-responsive G-protein-coupled receptor TGR5 is expressed in monocytes and macrophages, and plays a critical role in regulating inflammatory response. Our previous work has shown its role in promoting the progression of non-small cell lung cancer (NSCLC), yet the mechanism remains unclea...