Effects of valsartan on morphine tolerance and dependence in rats

• Main Authors: Ayat Kaeidi (Author), Morteza Amirteimoury (Author), Mohammad-Saleh Zare (Author), Amirhossein Nazari (Author), Elham Hakimizadeh (Author), Jalal Hassanshahi (Author), Iman Fatemi (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and purpose: Opiates are traditionally used for the treatment of pain. Chronic consumption of opiates such as morphine (MOR) induces tolerance and dependence. This study aimed to investigate the effects of valsartan (VAL), as an angiotensin II receptor blocker, on the induction and expres...