Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis

• Autores principales: Xiaowei Zhang (Autor), Ping Zhang (Autor), Lin An (Autor), Ningyuan Sun (Autor), Liying Peng (Autor), Weiwei Tang (Autor), Dingyuan Ma (Autor), Jun Chen (Autor)
• Formato: Libro
• Publicado: Elsevier, 2020-08-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Pyroptosis is a form of programmed cell death, and recently described as a new molecular mechanism of chemotherapy drugs in the treatment of tumors. Miltirone, a derivative of phenanthrene-quinone isolated from the root of Salvia miltiorrhiza Bunge, has been shown to possess anti-cancer activities....