Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alpha

• Główni autorzy: Guolin Li (Autor), Chad N. Brocker (Autor), Tingting Yan (Autor), Cen Xie (Autor), Kristopher W. Krausz (Autor), Rong Xiang (Autor), Frank J. Gonzalez (Autor)
• Format: Książka
• Wydane: Elsevier, 2018-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background: Peroxisome proliferator-activated receptor alpha (PPARA) is a major regulator of fatty acid oxidation and severe hepatic steatosis occurs during acute fasting in Ppara-null mice. Thus, PPARA is considered an important mediator of the fasting response; however, its role in other fasting r...