Mitochondria as an important target of metformin: The mechanism of action, toxic and side effects, and new therapeutic applications

• Hauptverfasser: Jin Feng (Verfasst von), Xiaohui Wang (Verfasst von), Xiaochun Ye (Verfasst von), Irma Ares (Verfasst von), Bernardo Lopez-Torres (Verfasst von), Marta Martínez (Verfasst von), María-Rosa Ma (Verfasst von), Xu Wang (Verfasst von), Arturo Anadón (Verfasst von), María-Aránzazu Martínez (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2022-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Metformin is the oldest and most commonly used first-line antidiabetic drug because of its good clinical efficacy, high safety, low cost and easy access. At the same time, in recent years, we have found that its role as a therapeutic drug is gradually expanding. A large number of basic studies have...