Assessment of syndecan-4 expression in the hearts of Trypanosoma cruzi-infected mice and human subjects with chronic Chagas disease cardiomyopathy

• Main Authors: Ticiana Ferreira Larocca (Author), Bruno Solano de Freitas Souza (Author), Carolina Thé Macêdo (Author), Carine Machado Azevedo (Author), Juliana Fraga Vasconcelos (Author), Daniela Nascimento Silva (Author), Diogo Crispim Nascimento Portella (Author), Washington Luis Conrado dos Santos (Author), Fabio Rocha Fernandes Tavora (Author), João David de Souza Neto (Author), Ricardo Ribeiro dos Santos (Author), Milena Botelho Pereira Soares (Author)
• Format: Book
• Published: BMC, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chronic Chagas cardiomyopathy (CCC) is characterized by the presence of a multifocal inflammatory response and myocardial damage, leading to fibrosis, arrhythmias and ventricular dysfunction. The expression of syndecan-4, a transmembrane proteoglycan, was previously found to be i...