CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection.

• Main Authors: Guang Xu (Author), Nicole L Mendell (Author), Yuejin Liang (Author), Thomas R Shelite (Author), Yenny Goez-Rivillas (Author), Lynn Soong (Author), Donald H Bouyer (Author), David H Walker (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scrub typhus, caused by a Gram-negative obligately intracellular coccobacillus, Orientia tsutsugamushi, is a long neglected but important tropical disease. Orientia tsutsugamushi causes illness in one million people each year, and 1 billion people are at risk. Without appropriate diagnosis and treat...