Newly discovered clouting interplay between matrix metalloproteinases structures and novel quaternary Ammonium K21: computational and in-vivo testing

• Main Authors: Ranjeet Ajit Bapat (Author), Kit-Kay Mak (Author), Mallikarjuna Rao Pichika (Author), Jia Chern Pang (Author), Seow Liang Lin (Author), Suan Phaik Khoo (Author), Umer Daood (Author)
• Format: Book
• Published: BMC, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aims and objectives To analyze anti-MMP mode of action of Quaternary Ammonium Silane (QAS, codenamed as k21) by binding onto specific MMP site using computational molecular simulation and Anti-Sortase A (SrtA) mode of action by binding onto specific site using computational molecular simula...