Alcohol-Induced Liver Injury Is Modulated by Nlrp3 and Nlrc4 Inflammasomes in Mice

Alcoholic liver disease (ALD) is characterized by increased hepatic lipid accumulation (steatosis) and inflammation with increased expression of proinflammatory cytokines. Two of these cytokines, interleukin-1β (IL-1β) and IL-18, require activation of caspase-1 via members of the NOD-like receptor (...

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Bibliographic Details
Main Authors: David A. DeSantis (Author), Chih-wei Ko (Author), Yang Liu (Author), Xiuli Liu (Author), Amy G. Hise (Author), Gabriel Nunez (Author), Colleen M. Croniger (Author)
Format: Book
Published: Hindawi Limited, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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