Facile Synthesis of <i>N</i>-(4-Bromo-3-methylphenyl)pyrazine-2-carboxamide Derivatives, Their Antibacterial Activities against Clinically Isolated XDR <i>S. Typhi</i>, Alkaline Phosphatase Inhibitor Activities, and Docking Studies

• Autores principales: Abdul Hannan Khan (Autor), Muhammad Bilal (Autor), Abid Mahmood (Autor), Nasir Rasool (Autor), Muhammad Usman Qamar (Autor), Muhammad Imran (Autor), Sebastian Ionut Toma (Autor), Oana Andreescu (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2024-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The emergence of extensively drug-resistant <i>Salmonella</i> Typhi (XDR-<i>S. Typhi</i>) poses a grave public health threat due to its resistance to fluoroquinolones and third-generation cephalosporins. This resistance significantly complicates treatment options, underscorin...