Simultaneous analysis of T helper subsets (Th1, Th2, Th9, Th17, Th22, Tfh, Tr1 and Tregs) markers expression in periapical lesions reveals multiple cytokine clusters accountable for lesions activity and inactivity status

• Main Authors: Ana Claudia ARAUJO-PIRES (Author), Carolina Favaro FRANCISCONI (Author), Claudia Cristina BIGUETTI (Author), Franco CAVALLA (Author), Andreza Maria Fabio ARANHA (Author), Ariadne LETRA (Author), Ana Paula Favaro TROMBONE (Author), Marcelo FAVERI (Author), Renato Menezes SILVA (Author), Gustavo Pompermaier GARLET (Author)
• Format: Book
• Published: University of São Paulo, 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Previous studies demonstrate that the balance between pro- and anti-inflammatory mediators determines the stable or progressive nature of periapical granulomas by modulating the balance of the osteoclastogenic factor RANKL and its antagonist OPG. However, the cytokine networks operating in the devel...