Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells

• Asıl Yazarlar: Juan Yan (Yazar), Li-Ping Ma (Yazar), Fang Liu (Yazar), Bo Sun (Yazar), Mei Tian (Yazar), Xue Lu (Yazar), Hai-Xiang Liu (Yazar), Ling Gao (Yazar), Qing-Jie Liu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: SAGE Publishing, 2022-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective To explore the effect and mechanism of ultraviolet B (UVB) on melanin synthesis and premature senescence in human immortalized keratinocytes (HaCaT) cells. Methods HaCaT cells were irradiated with 0, 20, 50, 80, 100, 150, and 200 mJ/cm 2 of UVB. NaOH method was used for melanin content ass...