Antidepressant-like drug effects in juvenile and adolescent mice in the tail suspension test: Relationship with hippocampal serotonin and norepinephrine transporter expression and function.

• Main Authors: Nathan C Mitchell (Author), Georgianna G Gould (Author), Corey M Smolik (Author), Wouter eKoek (Author), Lynette C Daws (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Depression is a major health problem for which most patients are not effectively treated. This problem is further compounded in children and adolescents where only two antidepressants [both selective serotonin reuptake inhibitors (SSRIs)] are currently approved for clinical use. Mouse models provide...