Alimentary Treatment with Trehalose in a Pharmacological Model of Alzheimer's Disease in Mice: Effects of Different Dosages and Treatment Regimens

• Main Authors: Alexander B. Pupyshev (Author), Anna A. Akopyan (Author), Michael V. Tenditnik (Author), Marina V. Ovsyukova (Author), Nina I. Dubrovina (Author), Victor M. Belichenko (Author), Tatiana A. Korolenko (Author), Svetlana A. Zozulya (Author), Tatiana P. Klyushnik (Author), Maria A. Tikhonova (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the treatment of experimental neurodegeneration with disaccharide trehalose, various regimens are used, predominantly a 2% solution, drunk for several weeks. We studied the effects of different regimens of dietary trehalose treatment in an amyloid-β (Aβ) 25-35-induced murine model of Alzheimer�...