NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1

• Main Authors: Jianjian Zhang (Author), Weibin Xie (Author), Bin Ni (Author), Zhuohang Li (Author), Dengyuan Feng (Author), Yao Zhang (Author), Qianguang Han (Author), Hai Zhou (Author), Min Gu (Author), Ruoyun Tan (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal interstitial fibrosis/tubular atrophy (IF/TA) is a prominent pathological feature of chronic allograft dysfunction (CAD). Our previous study has demonstrated that epithelial-mesenchymal transition (EMT) plays a significant role in shaping the development of IF/TA. Nuclear SET domain (NSD2), a...