NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1

• Hoofdauteurs: Jianjian Zhang (Auteur), Weibin Xie (Auteur), Bin Ni (Auteur), Zhuohang Li (Auteur), Dengyuan Feng (Auteur), Yao Zhang (Auteur), Qianguang Han (Auteur), Hai Zhou (Auteur), Min Gu (Auteur), Ruoyun Tan (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2024-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Renal interstitial fibrosis/tubular atrophy (IF/TA) is a prominent pathological feature of chronic allograft dysfunction (CAD). Our previous study has demonstrated that epithelial-mesenchymal transition (EMT) plays a significant role in shaping the development of IF/TA. Nuclear SET domain (NSD2), a...