Evaluation of the Biomarkers HMGB1 and IL-6 as Predictors of Mortality in Cirrhotic Patients with Acute Kidney Injury

• Main Authors: Célio Geraldo de Oliveira Gomes (Author), Marcus Vinicius Melo de Andrade (Author), Ludmila Resende Guedes (Author), Henrique Carvalho Rocha (Author), Roberto Gardone Guimarães (Author), Fernando Antônio Castro Carvalho (Author), Eduardo Garcia Vilela (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Acute kidney injury (AKI) affects from 20% to 50% of cirrhotic patients, and the one-month mortality rate is 60%. The main cause of AKI is bacterial infection, which worsens circulatory dysfunction through the release of HMGB1 and IL-6. Objectives. To evaluate HMGB1 and IL-6 as biomarker...