WBC count and functional changes induced by co-administration of clofazimine and clarithromycin, in single and multiple doses, in Wistar rats

• Egile Nagusiak: Flávia Aparecida Paina (Egilea), Julise Cunha Miranda (Egilea), Cristiane Fernandes de Freitas Tavares (Egilea), Regina Helena da Costa Queiroz (Egilea), Ana Maria de Souza (Egilea)
• Formatua: Liburua
• Argitaratua: Universidade de São Paulo, 2012-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Clofazimine and clarithromycin are used to treat leprosy and infections caused by Mycobacterium avium complex. Little data on the toxicity of co-administration of these two drugs are available. Here we evaluated the potential adverse effects of polytherapy with these two drugs in male Wistar rats by...