Transporter-Mediated Mitochondrial GSH Depletion Leading to Mitochondrial Dysfunction and Rescue with αB Crystallin Peptide in RPE Cells

Mitochondrial glutathione (mGSH) is critical for cell survival. We recently reported the localization of OGC (SLC25A11) and DIC (SLC25A10) in hRPE. Herein, we investigated the suppression of OGC and DIC and the effect of αB crystallin chaperone peptide co-treatment on RPE cell death and mitochondria...

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Main Authors: Parameswaran G Sreekumar (Author), Mo Wang (Author), Christine Spee (Author), Srinivas R. Sadda (Author), Ram Kannan (Author)
Format: Book
Published: MDPI AG, 2020-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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