Regulation of Immune Cell Infiltration into the CNS by Regional Neural Inputs Explained by the Gate Theory

• Main Authors: Yasunobu Arima (Author), Daisuke Kamimura (Author), Lavannya Sabharwal (Author), Moe Yamada (Author), Hidenori Bando (Author), Hideki Ogura (Author), Toru Atsumi (Author), Masaaki Murakami (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The central nervous system (CNS) is an immune-privileged environment protected by the blood-brain barrier (BBB), which consists of specific endothelial cells that are brought together by tight junctions and tight liner sheets formed by pericytes and astrocytic end-feet. Despite the BBB, various immu...