Injectable peptide hydrogel as intraperitoneal triptolide depot for the treatment of orthotopic hepatocellular carcinoma

• Main Authors: Xiyue Zhao (Author), Xiaoyu Liu (Author), Pengcheng Zhang (Author), Yiran Liu (Author), Wei Ran (Author), Ying Cai (Author), Junyang Wang (Author), Yihui Zhai (Author), Guanru Wang (Author), Yaping Ding (Author), Yaping Li (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemotherapy is among the limited choices approved for the treatment of hepatocellular carcinoma (HCC) at intermediate and advanced stages. Preferential and prolonged drug exposure in diseased sites is required to maximize the therapeutic index of the drug. Here, we report an injectable supramolecul...