Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling

• Główni autorzy: Merve Keles (Autor), Steve Grein (Autor), Natali Froese (Autor), Dagmar Wirth (Autor), Felix A. Trogisch (Autor), Rhys Wardman (Autor), Shruthi Hemanna (Autor), Nina Weinzierl (Autor), Philipp-Sebastian Koch (Autor), Stefanie Uhlig (Autor), Santosh Lomada (Autor), Gesine M. Dittrich (Autor), Malgorzata Szaroszyk (Autor), Ricarda Haustein (Autor), Jan Hegermann (Autor), Abel Martin-Garrido (Autor), Johann Bauersachs (Autor), Derk Frank (Autor), Norbert Frey (Autor), Karen Bieback (Autor), Julio Cordero (Autor), Gergana Dobreva (Autor), Thomas Wieland (Autor), Joerg Heineke (Autor)
• Format: Książka
• Wydane: Elsevier, 2024-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Pathological cardiac remodeling predisposes individuals to developing heart failure. Here, we investigated two co-regulated long non-coding RNAs (lncRNAs), termed Gadlor1 and Gadlor2, which are upregulated in failing hearts of patients and mice. Cardiac overexpression of Gadlor1 and Gadlor2 aggravat...