Improvement of irradiation-induced fibroblast damage by α2-macroglobulin through alleviating mitochondrial dysfunction

• Main Authors: Chaoji Huangfu (Author), Nan Tang (Author), Xiaokun Yang (Author), Zhanwei Gong (Author), Junzheng Li (Author), Junting Jia (Author), Jingang Zhang (Author), Yan Huang (Author), Yuyuan Ma (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context α2-Macroglobulin (α2-M) is believed to be a potential anti-irradiation agent, but related mechanisms remains unclear.Objective We investigated the irradiation protective effect of α2-M.Materials and methods A total of 10 Gy dose of irradiation was used to damage human skin fibroblasts. The i...