Downregulation of ICCs and PDGFRα+ cells on colonic dysmotility in hirschsprung disease

• Main Authors: Aiming Gu (Author), Zhihao Wu (Author), Peng Wang (Author), Jun Liu (Author), Jianfeng Wang (Author), Qianqian Wang (Author), Jie Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundTo investigate the effect of the distribution and expression of interstitial cells of Cajal (ICCs) and platelet-derived growth factor receptor-α positive (PDGFRα+) cells in different colon segments on colonic motility in children with Hirschsprung disease (HSCR).MethodsSmooth muscles of th...