Detection of Human Microchimerism following Allogeneic Cell Transplantation Using Droplet Digital PCR

• Main Authors: Catherine A. Lombard (Author), Alexandre Fabre (Author), Jérôme Ambroise (Author), Joachim Ravau (Author), Floriane André (Author), Nawal Jazouli (Author), Mustapha Najimi (Author), Xavier Stéphenne (Author), Françoise Smets (Author), Jean-Luc Vaerman (Author), Etienne M. Sokal (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Cell transplantation is in clinical development for the treatment of various ailments including acquired and inborn hepatic diseases. Detection and quantification of the donor cells after infusion remain difficult. Traditional methods (sex-based FISH, HLA mismatch, and Short Tandem Repea...