Impurity profiling method development and validation of metformin hydrochloride and teneligliptin hydrobromide hydrate in their combination tablet dosage form by using RP-HPLC with UV/PDA detector

• Egile Nagusiak: B. D. Musmade (Egilea), M. L. Baraskar (Egilea), V. N. Ghodke (Egilea), S. G. Bhope (Egilea), S. Padmanabhan (Egilea), K. S. Lohar (Egilea)
• Formatua: Liburua
• Argitaratua: SpringerOpen, 2021-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background An accurate, precise and robust analytical method was developed for the impurity profiling in the metformin hydrochloride and teneligliptin hydrobromide hydrate tablet. The gradient was optimized for better separation of impurities by using BDS Hypersil C18 250 × 4.6 mm, 5µ colum...