Triptolide Inhibits Osteoclast Differentiation and Bone Resorption In Vitro via Enhancing the Production of IL-10 and TGF-β1 by Regulatory T Cells

• Главные авторы: Huihui Xu (Автор), Hongyan Zhao (Автор), Cheng Lu (Автор), Qi Qiu (Автор), Gui Wang (Автор), Jing Huang (Автор), Minghui Guo (Автор), Baosheng Guo (Автор), Yong Tan (Автор), Cheng Xiao (Автор)
• Формат: ‌
• Опубликовано: Hindawi Limited, 2016-01-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Triptolide, a purified component of Tripterygiumwilfordii Hook F, has been shown to have immunosuppressive and anti-inflammatory properties in rheumatoid arthritis (RA). Although triptolide has demonstrated that it could suppress bone destruction in collagen-induced mice, its therapeutic mechanism r...