Retro-inverso follicle-stimulating hormone peptide-mediated polyethylenimine complexes for targeted ovarian cancer gene therapy

• Main Authors: Mengyu Zhang (Author), Mingxing Zhang (Author), Jing Wang (Author), Qingqing Cai (Author), Ran Zhao (Author), Yi Yu (Author), Haiyan Tai (Author), Xiaoyan Zhang (Author), Congjian Xu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The development of nanoparticle drug delivery systems with targeted ligands has the potential to increase treatment efficiency in ovarian cancer. Methods: We developed a 21-amino acid peptide, YTRDLVYGDPARPGIQGTGTF (L-FP21) conjugated to polyethylenimine (PEI) and methoxy polyethylene gl...