Novel Sulfonamide-Based Analogs of Metformin Exert Promising Anti-Coagulant Effects without Compromising Glucose-Lowering Activity

• Main Authors: Magdalena Markowicz-Piasecka (Author), Adrianna Sadkowska (Author), Joanna Sikora (Author), Marlena Broncel (Author), Kristiina M. Huttunen (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2020-10-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Metformin, one of the most frequently prescribed oral anti-diabetic drugs, is characterized by multidirectional activity, including lipid lowering, cardio-protective and anti-inflammatory properties. This study presents synthesis and stability studies of 10 novel sulfonamide-based derivatives of met...