A Set of Experimentally Validated Decoys for the Human CC Chemokine Receptor 7 (CCR7) Obtained by Virtual Screening

• Главные авторы: Matic Proj (Автор), Steven De Jonghe (Автор), Tom Van Loy (Автор), Marko Jukič (Автор), Anže Meden (Автор), Luka Ciber (Автор), Črtomir Podlipnik (Автор), Uroš Grošelj (Автор), Janez Konc (Автор), Dominique Schols (Автор), Stanislav Gobec (Автор)
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• Опубликовано: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Предметы: article
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We present a state-of-the-art virtual screening workflow aiming at the identification of novel CC chemokine receptor 7 (CCR7) antagonists. Although CCR7 is associated with a variety of human diseases, such as immunological disorders, inflammatory diseases, and cancer, this target is underexplored in...