Pharmacokinetic and Pharmacodynamic Integration and Resistance Analysis of Tilmicosin Against Mycoplasma gallisepticum in an In Vitro Dynamic Model

• Main Authors: Zilong Huang (Author), Yuzhi Wu (Author), Zichong Zhou (Author), Xirui Xia (Author), Xiaoyan Gu (Author), Qinren Cai (Author), Xiangguang Shen (Author), Hong Yang (Author), Huanzhong Ding (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycoplasma gallisepticum is the major pathogen causing chronic respiratory disease in chickens. In the present study, we successfully established a one-compartment open model with first-order absorption to determine the relationship between tilmicosin pharmacokinetic and pharmacodynamic (PK/PD) indi...