Evaluation of Actinium-225 Labeled Minigastrin Analogue [²²⁵Ac]Ac-DOTA-PP-F11N for Targeted Alpha Particle Therapy

• Asıl Yazarlar: Yun Qin (Yazar), Stefan Imobersteg (Yazar), Alain Blanc (Yazar), Stephan Frank (Yazar), Roger Schibli (Yazar), Martin P. Béhé (Yazar), Michal Grzmil (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The overexpression of cholecystokinin B receptor (CCKBR) in human cancers led to the development of radiolabeled minigastrin analogues for targeted radionuclide therapy, which aims to deliver cytotoxic radiation specifically to cancer cells. Alpha emitters (e.g., actinium-225) possess high potency i...