A Pair of Siblings With Wolfram Syndrome: A Review of the Literature and Treatment Options

• Main Authors: Doanna Png MD (Author), Ester Yeoh MBBS, MRCP, M.Med, FAMS, FRCP (Author), Clara Tan MSc (Author), Su Chi Lim MBBS, MRCP, FRCP, FAMS, PhD (Author)
• Format: Book
• Published: SAGE Publishing, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Wolfram syndrome (WS) is a rare genetic disorder typically characterized by juvenile onset diabetes mellitus, optic atrophy, hearing loss, diabetes insipidus, and neurodegeneration. There would be a high index of clinical suspicion for WS when clinical manifestations of type 1 diabetes and optic atr...