Ocular Pharmacological Profile of Hydrocortisone in Dry Eye Disease

• Main Authors: Claudio Bucolo (Author), Annamaria Fidilio (Author), Claudia Giuseppina Fresta (Author), Francesca Lazzara (Author), Chiara Bianca Maria Platania (Author), Giuseppina Cantarella (Author), Giulia Di Benedetto (Author), Chiara Burgaletto (Author), Renato Bernardini (Author), Cateno Piazza (Author), Stefano Barabino (Author), Filippo Drago (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To investigate the ocular pharmacological profile of hydrocortisone (HC) using in vitro and in vivo models of dry eye disease. Rabbit corneal epithelial cells (SIRCs) were used to assess the effect of HC in two paradigms of corneal damage: hyperosmotic stress and scratch-wound assay. Dry eye was ind...