Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis.

• Hoofdauteurs: Britta Stadelmann (Auteur), Reto Rufener (Auteur), Denise Aeschbacher (Auteur), Markus Spiliotis (Auteur), Bruno Gottstein (Auteur), Andrew Hemphill (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2016-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The metacestode (larval) stage of the tapeworm Echinococcus multilocularis causes alveolar echinococcosis (AE), a very severe and in many cases incurable disease. To date, benzimidazoles such as albendazole and mebendazole are the only approved chemotherapeutical treatment options. Benzimidazoles in...